Changing Epidemiological Patterns and High-Risk Sexual Behaviour among HIV-Syphilis Coinfected Individuals: A Case Series from Chandauli District, Eastern Uttar Pradesh
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Abstract
HIV–syphilis co-infection is facilitated by shared transmission routes and biological interactions, yet data from rural Eastern Uttar Pradesh remain limited. We retrospectively reviewed records of four individuals with confirmed co-infection from Chandauli district, focusing on clinical, behavioural, laboratory, treatment, and follow-up characteristics. Cases were detected through dental, community-based, and medical screening and showed varied clinical presentations. CD4 counts ranged from 170–286 cells/µL; hepatitis B co-infection, poor antiretroviral therapy adherence, and loss to follow-up were documented. The findings highlight the importance of opportunistic screening, partner services, inclusive sexual-health assessment, and sustained linkage to care in rural settings.
Keywords: HIV, Syphilis, High risk behaviour.
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