A review study on pathogenesis, symptoms, diagnosis, and treatment options of chordoma

Abstract

Cancers are result of uncontrolled division of cells that affect the normal activity of organ. Cancer are classified according to origin organ. Chordoma (notochordal sarcoma) is slowly progressing tumor of spine. These tumors may develop at any part of spinal cord but mostly develops near the tail bone also called as sacral tumor. Most common type of chordoma are cranial chordoma, sacral chordoma, and spinal chordoma. The common sites for this cancer are sacrum, skull base, and spine. These are diagnosed in about 1 individual in 1 million people every year.  These tumors develop in late age and demonstrate poor prognosis. Including this, these tumors also create many challenges to treat. The most common ways to diagnose chordoma are biopsy, magnetic resonance imaging, and computed tomography imaging. In this review article, we have briefly discussed the pathophysiology, diagnosis, and treatment options of chordoma. Including this, other approaches for treatment of chordoma are also discussed.

Keywords: Cancer; Chordoma; Chordoma Diagnosis; Chordoma Risk Factors; Chordoma Treatment