Prevalence and Management of Mucormycosis in India- A Post Pandemic Analysis

Abstract

Background: The emergence of SARS-CoV-2 has increased Mucormycosis cases, which was perceived to be a rare infection caused by belligerent fungi belonging to order Mucorales. It is also called the black fungus and is exhibited as one of the seven variants such as rhino-cerebral, cutaneous, pulmonary, renal, gastrointestinal, disseminated or miscellaneous, leading to the debilitation of systemic wellness often associated with a reduction in functional efficiency and characterized by organ failure due to necrosis necessitating early diagnosis and timely treatment.

Aim: Hence, to sustain the quality of life during the pandemic, this review was aimed for a better understanding of Mucormycosis which is the need of the hour for efficient management to overcome global crises.

Materials and Methodology: A theoretical review was carried out on existing literature over three decades involving data in India as well as its global comparison, especially in terms of incidence and prevalence for enabling a scientifically evidence-based comprehensive analysis.

 Results: Indians have higher risk to Mucormycosis due to its large diabetic population when compared globally. It is evident that the rhino cerebral variant is the most commonly prevalent with a recent surge due to the pandemic. Conclusion: Both the incidence and prevalence of mucormycosis cases in India have always been very higher and has escalated even further due to the outbreak of SARS-CoV-2. It is recommended that appropriate modalities have to be adopted in individuals with immunocompromised conditions to safeguard them from contracting any reinfection as they are more susceptible to high-risk exposure.