Estimation of Factors Influencing Pregnancy Rates In intrauterine Insemination

Abstract

Introduction: Around 10-15 % of couples with infertility reported in outpatient department, intrauterine insemination has long been used and is considered as low cost, effective accessible approach to majority of patients when compared with other assisted methods. Aims: To estimate the factors influencing success rate of Intra uterine insemination. Methodology: It is a prospective descriptive study done over a period of 2 years from October 2020 to September 2022 at infertility clinic, Jay kay lon hospital over 66 patients. All eligible women were given ovulation induction with intra uterine insemination and followed up. Results: Mean age of participants was 31 years, pregnancy rate was 15.2%, out of 66, 10 conceived women, 1 was ectopic gestation,4 aborted, 5 carried pregnancy till term. Pregnancy rate of 4.54% with one follicle and 10.65% with two follicles observed with the cut off follicular size 16 mm. The mean endometrial thickness in the conceived group was found 9.38mm. 4 patients conceived with 1 IUI cycle , 4 patients with 2 IUI and 2 patients with 3 IUI cycles respectively.9 patients conceived with the total motile sperm count of20-30 million/ml. Conclusion: IUI is a low-cost technique with basic supplies, simple training and accessible for majority of couples seeking infertility treatment. Amongst variable factors studied, the mean endometrial thickness, follicular number, the dominant follicle size, total motile sperm count and total number of UI cycles were found statistically significant.

Keywords:  Infertility, intrauterine insemination, pregnancy .