INFLUENCE OF STORAGE CONDITIONS AND PRESERVATIVES ON URINALYSIS
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Abstract
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Introduction: Urinalysis is very susceptible to pre-analytical issues, one of which arises due to improper or no preservation of urine samples before analysis. Thymol as a preservative because of its antimicrobial property has the advantage of preserving glucose and sediments well. The current study is to evaluate how different concentrations of preservative (thymol) used for storage of urine samples affected the outcome of urine analyses. Material and methods: Spot urine samples were collected from 507 volunteers. Each fresh sample of urine was divided into three 10 ml aliquots, one without preservative, one with 1 drop of thymol and one with 2 drops of thymol. Each urine sample was analysed immediately after collection (0 hour) and after 24 hours. Conclusion: Antibacterial preservatives like thymol can be recommended as preservatives for urine samples taking more than 2 hours. Ideally, the samples can be stored at 4 °C without any preservatives.
KEYWORDS: Thymol, preservatives, urinalysis.