Cerebral venous thrombosis study of a series of 20 cases

Abstract

Summary:

Objective: The aim of our work is to study the clinical, risk factor and evolutionary characteristics of cerebral venous thrombosis (CVT) in our series and compare it with data from the literature.

Methods: This is a retrospective study including 20 patients hospitalized and followed up in the neurology department of the Moulay Ismail military hospital in Meknes.The diagnosis of CVT was confirmed in all patients by magnetic resonance imaging (MRI) with magnetic resonance venography (MRV), and/or cerebral CT scan with computed tomography venography (CTV).

Clinical and biological risk factors for CVT were analysed.The average follow-up was 12 months (6 to 18 months) and evolution was evaluated clinically and radiologically.

Results: In our serie, the mean age was 32.6 years with a predominance of females (sex ratio of 4Women/1Men). The clinical was subacute in 70% of cases.The inaugural signs were essentially represented by headaches.Topographically, superior longitudinal sinus thrombosis was the most common, estimated at (70%).Parenchymatous lesions were observed (45%), mainly of haemorrhagic infarction type (30%).Etiologically, thrombophilia and gynaeco-obstetrical  causes were predominant with a respective prevalence of 50% and 40 % .In 80% cases, the evolution was good, with heparin therapy relayed by anti-vitamin K coupled with etiological treatment as needed.

Conclusion: The characteristics of CVT in our study stands out from the data in the Western literature by a high frequency of thrombophilia and gynaeco-obstetrical causes.