Proportion of Guillain Barre syndrome and their outcome among children presenting with acute flaccid paralysis

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Dr. Dixita Patel1, Dr. Dhruvin Doshi 2, Dr. Deval Surana3

Abstract

Background: Guillain Barre syndrome ( GBS) is a common cause of acute flaccid weakness in children with long term morbidity in term of poor functional outcome.


Aim: To estimate the frequency of GBS and to determine contributing factors for poor functional outcome.


Methods: Retrospective study. Two year data of children presented with acute flaccid paralysis ( AFP) were retrieved from hospital records. Outcome measures of GBS were need for mechanical ventilation ( MV), mortality and functional status at 6 month.


Results: Out of 47 cases of AFP, 39 (83%) had GBS. Summer season witnessed lowest number of cases. Median age of GBS patient was 9 year, 64% males. At presentation 80% had disability score>=3. AMAN (49%) most common subtype. 28% patient needed MV. Mortality was 15%. Out of 33 survived patient ,11 (33.33%) had poor functional outcome at 6 month. High disability score ( p o.o49), long duration between symptom onset and admission ( p 0.047), rapid progression ( p 0.03) and AMAN variety ( 0.0045) were associated with poor outcome.


Conclusion: Long term disability is common in children having GBS. Axonal type of nerve injury is poor predictive factor both for mortality and functional outcome.

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How to Cite
Dr. Dixita Patel1, Dr. Dhruvin Doshi 2, Dr. Deval Surana3. (2024). Proportion of Guillain Barre syndrome and their outcome among children presenting with acute flaccid paralysis. International Journal of Medical Science in Clinical Research and Review, 7(02), Page: 310–316. Retrieved from http://ijmscrr.in/index.php/ijmscrr/article/view/739