Histomorphological Spectrum of Soft Tissue Tumours at A Tertiary Care Hospital In Garhwal Region: A Retrospective Study.

Abstract

Background: Soft tissue tumours are defined as tumours of non-epithelial, extra skeletal tissues of the body excluding central nervous system, and haematolymphoid tissue. It includes muscular, fibrous, elastic, vascular and adipose tissue. Tumours arising from peripheral nerves as soft tissue masses are also included in soft tissue tumours. It is a heterogenous group of tumours that are classified on the histogenetic basis of the adult tissue they resemble. Method: All the histopathology sections diagnosed as soft tissue tumours from January 2019 to December 2023 in the Department of Pathology of our tertiary care hospital were analysed. A total of 325 cases were reported. The microscopic findings of the histological sections of these cases were studied in detail in Haematoxylin and Eosin stain. Histological subtyping of these tumours was done according to WHO classification of soft tissue tumours 2022. Conclusion: The peak age of incidence of soft tissue tumours was between 3^rd to 4^th decades of age with female to male ratio of 1.4:1. Benign tumours (89.5%) are more common than malignant tumours (5.5%). Most common soft tissue tumour is Lipomatous tumour.

Keywords: Haemangioma, Mesenchymal tumours, Leiomyoma, Lipoma, Sarcoma, Soft tissue tumour.