To Determine Vitamin D, Cholesterol, Triglycerides, HDL, LDL, and VLDL Play Roles in Pre- and Post-Menopausal Women with Type 2 Diabetes.

Abstract

The two most common long-term health issues that cause cardiovascular disease in women after menopause are glucose homeostasis and abnormal vitamin D levels. An increased risk of type 2 diabetes mellitus (T2DM) may be linked to insufficient vitamin D levels. Vitamin D level in connection to glycemic indices and metabolic parameters was examined in this study of premenopausal and postmenopausal women with type 2 diabetes. Using SPSS software, researchers compared premenopausal and postmenopausal type 2 diabetic women by measuring their fasting blood glucose, lipid profile, and vitamin D levels. Serum levels of HDL-C and vitamin D fell considerably in postmenopausal T2DM women compared to the premenopausal group, while levels of FBG, TC, TAG, LDL-C, increased significantly (p<0.001). At p<0.05, there was a negative correlation between vitamin D and LDL-C. There was a robust inverse relationship between low vitamin D levels and metabolic or lipid parameters. While low HDL-C levels are associated with menopause, this study revealed no correlation between low HDL-C and low vitamin D levels in postmenopausal type 2 diabetic women. The current analysis delves at the link between vitamin D and cholesterol. Postmenopausal women with type 2 diabetes who also have dyslipidemia are at an increased risk for cardiovascular illnesses, according to this study's results.

Keywords: Type 2 Diabetes Mellitus, Menopause, glucose homeostasis, vitamin-D, Glycemic indices.