Heart Transplantation in Neonate and Childs with Congenital Heart Disease and Hypoplastic Left Heart Syndrome

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Délio Tiago Martins Malaquias¹,²,³;
Wellington da Silva Pereira da Cunha ²;
Gustavo Lopes dos Santos ²;
Fernando Pellegrini Ferraz ³,⁴;
Mariana Cury Sobreira ³,⁵;
Juliana Paschoal ²,⁶;
Laura Yurico Mizuno ³,⁷;
Suely Fernandes dos Santos ³,⁸;
Ana Clara Rabelo ³, ⁸,⁹;
Adriana lobo de Oliveira ³,¹º;
Ciro Martins de Abreu¹¹;
Marina da Rocha Souza ³,⁸;
Flávia Aureliano Luccas ³,¹º,¹²;
Liliana Martins Occulate ³,¹³;
Camila Anastácio da Silva ³,¹⁴;
Caroline Leite Fogaça ³,¹⁵;
Pâmela do Nascimento³,¹⁶;
Geizon Lee Ed Ames Ferreira de Oliveira ³,¹⁶,¹⁷;
Matheus Guedes Fernandes Silva ³,¹⁸;
Thiago Augusto Rochetti Bezerra ², ¹⁹.

Abstract

Introduction: There may be several causes for the main congenital heart defects. Genetic factors and maternal factors, including poorly controlled chronic diseases such as diabetes or phenylketonuria. Heart transplantation is the gold standard surgical approach for treating heart failure. Objectives: To carry out a literature review on the physiological processes of heart transplantation in neonates with congenital heart disease, and to verify the main indications and contraindications for heart transplantation. Material and Methods: This article is a literature review, based on the methodology that sought to identify the physiological processes of heart transplantation in neonates with congenital heart disease through the analysis of pre-performed studies, and thirty-three (33) articles were selected for the preparation of this literature review. Results and discussion: Heart transplantation in children has become an option in complex congenital heart diseases and cardiomyopathies refractory to conventional therapy. Diagnostic research into the etiology of heart disease has advanced in the last decade, which significantly increases the chances of survival for children with congenital heart dysfunction.  Another cardiac complication is babies with hypoplastic left heart syndrome. Final considerations: The shortage of organ donors is still a major obstacle to transplantation in Brazil. Even in cases where the organ can be obtained from a living donor, the number of transplants is small compared to the demand from patients waiting for surgery.

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How to Cite
Délio Tiago Martins Malaquias¹,²,³;, Wellington da Silva Pereira da Cunha ²;, Gustavo Lopes dos Santos ²;, Fernando Pellegrini Ferraz ³,⁴;, Mariana Cury Sobreira ³,⁵;, Juliana Paschoal ²,⁶;, Laura Yurico Mizuno ³,⁷;, Suely Fernandes dos Santos ³,⁸;, Ana Clara Rabelo ³, ⁸,⁹;, Adriana lobo de Oliveira ³,¹º;, Ciro Martins de Abreu¹¹;, Marina da Rocha Souza ³,⁸;, Flávia Aureliano Luccas ³,¹º,¹²;, Liliana Martins Occulate ³,¹³;, Camila Anastácio da Silva ³,¹⁴;, Caroline Leite Fogaça ³,¹⁵;, Pâmela do Nascimento³,¹⁶;, Geizon Lee Ed Ames Ferreira de Oliveira ³,¹⁶,¹⁷;, Matheus Guedes Fernandes Silva ³,¹⁸;, & Thiago Augusto Rochetti Bezerra ², ¹⁹. (2023). Heart Transplantation in Neonate and Childs with Congenital Heart Disease and Hypoplastic Left Heart Syndrome . International Journal of Medical Science in Clinical Research and Review, 6(06), Page: 1051–1060. Retrieved from http://ijmscrr.in/index.php/ijmscrr/article/view/643