A Comparative Study for Tramadol Gargle and 2% Lidocaine Plain Solution for the Prevention of Postoperative Sore Throat Following General Anesthesia with Endotracheal Entubation in Patients Undergoing Ceasarean Section

Abstract

Background: The occurrence of postoperative sore throat after General anesthesia has been reported to have an incidence of up to 12%.  The highest risk factors for individuals undergoing tracheal intubation include being female, younger age, having previous larynx and trachea illness, longer anesthetic duration, traumatic intubation, and the presence of a blood-stained tracheal tube during extubation. Aim of study: To compare the efficacy of tramadol lavage and 2% lidocaine normal solution in treating postoperative sore pharynx following general anesthesia with endotracheal intubation. Patient and methods: 90 patient ASA class II, Female, Age between (18‐40), scheduled for Cesarean Section C/S requiring General Anesthesia with endotracheal intubation were randomly recruited into 3 groups: group A (tramadol), group B (2%xylocain plain solution), group C (tape water 30cc). Group A received tramadol gargle [ 100 mg in 30 ml tape water] for 2min, while group B received 2% plain solution lidocaine(2mg/kg) in 30 ml tape water gargled for 2min and group C received 30ml tape water was gargled for 2 min before induction of anesthesia. the incidence and severity of Postoperative sore throat were graded at 0,1,6 hr after surgery using four points ‐scale. Result: the incidence and severity of POST was significantly less in group A(tramadol group) in compared with group B (2% xylocaine plain solution)and group C (tap water) at grade zero,1hr . No statistically significant association (P= 0.108) between study groups and development of postoperative sore throat after six hours

Conclusion: study demonstrated that preoperative gargling with tramadol will decrease the incidence and severity of POST in compared to gargling with 2%xylocain plain solution in patient undergoing cesarean section C/S during general anesthesia with endotracheal intubation in the early postoperative period.

Keywords: post‐operative sore throat, tramadol gargling, xylocaine 2% plain solution.