CLINICAL PRESENTATION AND TREATMENT OUTCOMES IN PATIENTS OF LIVER ABSCESS IN NORTH INDIAN POPULATION

Abstract

BACKGROUND: Pyogenic and amoebic liver abscesses are rare, potentially lethal conditions. In this study, we aimed to To study the clinical presentation of patients with liver abscess. To study the overall outcome (morbidity and mortality). METHODS: Patients with confirmed liver abscesses were divided into three groups: amoebic group (n = 104), pyogenic (n = 41) and mixed group (n=4) which were analyzed for differences in clinical and laboratory findings. RESULTS: Amoebic liver abscesses presented most frequently in young adults (21 - 30 years; 33.6%), whereas pyogenic liver abscesses were most commonly observed in adults 41 - 50 years (26%). Pus culture reports of all Amoebic liver abscesses were reported as sterile. Most common organism isolated pyogenic liver abscess was E coli. CONCLUSIONS: Pyogenic abscesses were commonly observed in older patients, and were associated with features such as markedly deranged liver function test, leukocytosis, high PT/INR levels, longer hospital stay and higher complication and mortality rate compare to Amoebic liver abscess.

Keywords: Amoebic liver Abscess, Pyogenic Liver Abscess, Entamoeba histolytica