TO STUDY ON LOW BACK PAIN AND ITS ASSOCIATION WITH LEVELS OF VITAMIN D3.

Abstract

Background: Low back pain (LBP) is the highest contributor to disability worldwide, with current intervention strategies only providing small to moderate analgesic effects. The use of vitamin D supplementation for LBP has gained interest due to its proposed anti-inflammatory and neuro modulatory properties. However, it is still unclear whether vitamin D levels differ between those with and without LBP or if vitamin D levels are associated with pain intensity.

Objectives: We aim to investigate the association between vitamin D levels and LBP and to determine if vitamin D levels correlate with pain intensity in individuals with LBP.

Study Design: This study was conducted in accordance with the guidelines for performing a Meta analysis and Systematic Review of Observational Studies in Epidemiology (MOOSE).

_{Materials and Methodology:} A prospective observational study done at department of orthopaedics at simmer hospital(tertiary care hospital), surat conducted to study on low back pain and its association with levels of vitamin D_3. 197 patients were collected using the purposive sampling technique between August 2021 to October 2022.

Results: The patients' ages ranged from 31 to 40 years on average, with a mean age of 35.31 years and a standard deviation of 11.92 years (range: 18 to 60 years).A greater proportion of men (58.4%) were included in the study than women (41.6%), according to the population breakdown.62.9% of the 197 patients who suffered from chronic low back pain had inadequate levels of vitamin D₃, 16.8% had insufficient levels, and 20.3% had acceptable levels of vitamin D₃.The mean of vitamin D₃ in the study population was 20.9 ng/mL, with a standard deviation of 19.9 (range: 3.9 to 48.5 ng/mL).The average amount of vitamin D₃ found in females was 19.96 with a standard deviation of 13.11, And the results were as follows: 21.57 12.69 .There was a statistically significant inverse connection between the levels of vitamin D₃ and the MODQ score (p 0.05).

Conclusion: This study's findings provide information regarding the significant frequency of vitamin D₃ deficiency in the Indian population with chronic low back pain, which is associated with diminished functional capacity. Clinical guidelines for the management of chronic low back pain should include an evaluation of the patient's vitamin D₃ status, along with recommendations for appropriate vitamin D₃ supplementation for individuals who are found to be deficient in vitamin D₃.

Key words: Lower back pain, vitamin d3, VAS score , MODQ score.