A study on clinical and biochemical profile of covid-19 patients receiving oxygen therapy requiring ventilatory support in a tertiary care centre

Abstract

Aim:  This study was conducted to document different clinical and biochemical profiles of covid-19 patients admitted with oxygen support who later become ventilator dependent in Sri Venkateshwaraa medical college and Research institute, Ariyur.

Objectives:

To study the clinical and biochemical profile of covid-19 patients receiving oxygen therapy who requires ventilator support. To assess various parameters in terms of CRP, FERRITIN, D-DIMER levels on Admission and on ventilatory support .  Association between SPO2 with CRP,FERRITIN, D-DIMER and mode of ventilation.

Materials and Method:

This is a retrospective study of all patients admitted to Sri Venkateshwaraa Medical college hospital between March 01, 2021 and June 30, 2021, with the diagnosis of COVID-19 receiving oxygenon admission who ort later becomes ventilator dependent. From a common database prepared for COVID-19, we retrieved the relevant data and compared the clinical findings, biochemical parameters and outcomes of covid ward and covid ICU patients.

Results:

A total of 50 COVID -19 patients, aged 18 years and above, data were documented. There is a significant difference in biochemical values of the same patients while on Admission and on ventilator. Clinical parameters were associated with the risk covid -19 severity, but there was no statistically significant difference.

Key words: COVID 19, CRP, D-Dimer , Sr.Ferritin.