COVID 19 INFECTION IN PREGNANT FEMALE: CLINICAL SPECTRUM AND FETO-MATERNAL OUTCOME

Abstract

Background and Objective-COVID19 is caused by SARS CoV-2 strain of coronavirus. Our objective was to study the complete clinical spectrum and feto-maternal outcome in pregnant females with Covid 19 infection. Methods-This is a retrospective study, including pregnant women with confirmed COVID 19 infection. Data was collected and analysed with regard to clinical spectrum of covid 19 infection and feto-maternal outcome. Results- Clinical spectrum of covid 19 infection in pregnancy included, Asymptomatic (20%), mild (30%), moderate(30%)  and severe infection(20%). The mean maternal age was 30.9 years. Out of total patients 20 % was primigravida. Among all patients covid infection during third trimester occurred in 80%. 70% was term delivery, 30% was preterm deliveries, out of which 66.67% was iatrogenic preterm. Mode of delivery was LSCS in 70% out of which 57% was emergency LSCS for obstetric indication (85.7%), and in 14.28% cases emergency LSCS was done for severe maternal covid 19 pneumonia. Fetal outcomes were Mean birth weight- 2.65 kg, Median APGAR score at 1min and 5 min was 7 and 8 respectively. There was neither any evidence of vertical transmission nor prolonged NICU stay due to maternal covid infection in our study. Conclusion-Feto-maternal outcome is good in asymptomatic as well as in mild to moderate covid 19 infection. Patients with severe disease had increased maternal morbidity with adverse Fetal outcome in the form of fetal hypoxia and iatrogenic preterm delivery.