Clinical profile and prognostic indicators of septicemia: A descriptive observational study from Inlaks and Budhrani Hospital, Pune

Abstract

Background: The World health organisation and world health assembly have declared sepsis as a public health problem. Sepsis is major word wide cause of morbidity and mortality and causes a large burden of disease with negative impact in a community. Important aspects of sepsis management are early diagnosis as well as timely and specific treatment (e.g., antibiotics) in the first few hours of triage. Objective: To study the clinical course of septicaemia cases and to determine the prognostic factors of septicaemia. Methodology: It is a descriptive observational study carried out at ICU and IPD of Department of General Medicine, Inlaks and Budhrani Hospital, Pune during October 2014 -April 2016 involving 100 cases of septicaemia. Results: Majority of the cases were from above 70 years age group i.e. 16% males and 12% females. Most common causes of sepsis as per our study are pneumonia (22%). We observed significant association between temperature and MODS score in our study. There was significant association between MODS score and hypotension. We observed significant association between MODS score and mortality in our study. Conclusion: APACHE II and MODS score both have a strong significance with the mortality rates in sepsis.

Key words: Septicaemia, sepsis, clinical profile, APACHE 2, MODS etc