Primary amyloidosis of vocal cord masquerading as malignancy- a rare presentation Primary amyloidosis of vocal cord Section Original Research Paper

Abstract

Objective- To study role of histopathological examination for confirmation of Primary Amyloidosis of vocal cord and to differentiate the same from malignancy.

Case report- Here, we present a case of isolated laryngeal amyloidosis in adult female which mimics malignancy clinically.  Amyloidosis is gradual in onset and has unpredictable manner. It is a benign, heterogeneous, multisystem organ disorder affecting many tissues and organs. More commonly it affects kidney, Spleen, Liver, Heart, tongue along with many endocrine organs. However, Primary involvement of larynx is a very rare phenomenon in clinical settings. Isolated amyloidosis of vocal cord is a rare entity in clinical practice with only 0.2 to 1.2% of benign tumors of larynx.

Conclusion-Amyloidosis commonly mimics malignancy in clinical settings. Hence, it is mandatory to diagnose it accurately as it affects the treatment.