Acute Necrotising Pancreatitis: Clinical evaluation, Management and outcome in admitted patients at GSL Medical College, Rajahmundry

Abstract

Background: Acute Necrotizing pancreatitis (ANP) is the most lethal disease with poor prognosis, infected necrosis with a mortality rate of 30-39%, which is the major cause of death. The most widely used modality of treatment for infected necrosis has been open surgical necrosectomy, but it with high morbidity (34-95%) and mortality (11-39%).

Objective: To study the clinical presentation, management and outcome amongst admitted patients of Acute Necrotising Pancreatitis.

Methodology: The present hospital-based Prospective study was carried out at Department of General Surgery, GSL Medical College & Hospital, Rajahmundry involving 50 patients of acute necrotizing pancreatitis during the period of October 1ST, 2018, to September 30th, 2019.

Results: Majority of acute necrotizing pancreatitis patients were belonging to the 31-40 years age group (46%). Majority of the patients had pain in abdomen i.e. 96%. Ethanol (alcohol) was the most common etiology of acute necrotizing pancreatitis (50%), majority of the cases in our study had a CTSI score of 10 (54%). 33 cases (66%) were managed conservatively.

Conclusion: Our study demonstrates that the most common presentation of acute necrotizing pancreatitis is pain abdomen, with male predominance in the 30th decade of life. Ethanol (alcohol) was the most common etiology of acute necrotizing pancreatitis (50%). Conservative treatment of ANP with sterile necrosis is safe and effective.